For the past seven years, Siemens Cities Center of Competence (CoC) has been collaborating with more than 15 cities across North America to support Chief Sustainability Officers in evaluating technology and infrastructure options for deep carbon reduction. This report synthesizes results from those studies, sharing best practices, lessons learned, and trends in results, which can be used by any city in North America. The report includes work done with the Siemens City Performance Tool (CyPT), which was discussed during GPSC Expert Meeting “Measuring the Impact of Urban Planning Strategies on GHG Emissions” convened in April 2018.